Two Variants of Staphylococcus Aureus Wood 46 (nctc 7121) Differing in Respect to Alpha Toxin Production.
نویسنده
چکیده
منابع مشابه
Suppression of Staphylococcus aureus extracellular nuclease and alpha-toxin synthesis by acetylmethylcarbinol.
Acetylmethylcarbinol added to the inoculated culture of Staphylococcus aureus Wood 46 suppressed 85% of the differential rates of extracellular nuclease and alpha-toxin.
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The staphylococcal alpha-toxin (Hla) is a major virulence factor contributing to Staphylococcus aureus pathogenesis. To elucidate the conditions influencing hla expression, the determinant was fused to lacZ, the reporter gene coding for beta-galactosidase. The hla::lacZ fusion was integrated into the chromosome of the wild-type S. aureus strain Wood 46, leading to the variant Wood 46-3. Alpha-t...
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A cholesteryl de-esterifying enzyme found in partially purified preparations of alpha toxin produced by the Wood 46 strain on Staphylococcus aureus has been separated from other staphylococcal proteins and from alpha toxin by isoelectric focusing and gel filtration. Preparations of alpha toxin from Bi-Gel P-60 columns and of the cholesteryl esterase from Bio-Gel P-200 columns showed a high degr...
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عنوان ژورنال:
- Journal of bacteriology
دوره 86 شماره
صفحات -
تاریخ انتشار 1963